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Shvoong Home>Books>Novel Drug Delivery System Review

Novel Drug Delivery System

Book Review   by:kanya     Original Author: yie W Chien
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The novel drug delivery system second edition is a compilation of all important research carried out in the field of drug delivery science till the date of its publication in 1992.The book has twelve chapters where first two is devoted to the most important aspect -- the concepts of drug delivery and the latter ones explains in great detail the scientific rationale as well as technological aspects of specific delivery routes- oral,parenteral,transdermal , nasal, intrauterine, vaginal etc. What is a Novel Drug Delivery System:? Drugs are active substances which bind with the receptors usually located deep within the body – (to particular cells or tissues) to alter the unwanted physiological process that create disease. Sometimes the scientists come across the right chemical or natural products that can bind to the receptor and control an unwanted physiological process in insolated tissue or cells but fail to reach the target tissue in adequate quantity when administered in a functioning living systems. Novel drug delivery is a vital research area which strive to solve this problem and aim to achieve a programmed delivery of the therapeutic substances for the optimal beneficial effects while avoiding the side effect of drugs. How successful this research activity is? This branch of pharmaceutical research involves sophisticated technology and both animals and human life and is a costly affair.
Usually sponsored by industries, who, to retrieve their investment often protect the findings under patents. However publications in the scientific journals are valuable source for information and are discussed in detail by the author. It seems that in many fields particularly sustained release oral delivery, significant achievements have been done, many new products are appearing in this area. But the focus of future medicine will be biotechnological where drug products are proteins. Since the protein drugs get digested in gut, novel delivery route is a must for their therapeutic application. Several microinjection techniques and non-invasive transdermal route are getting currently investigated for the same. The author, a pioneering worker in the field of Transdermal Drug Delivery has discussed the basic concepts of this high- tech delivery mechanism iontophoresis ,sonophoresis , etc in great detail. What is high point of the book? The book clarifies some complicated concepts like feedback regulation and Activation Modulated Drug Delivery with clarity using examples that is of substantial help to the pharmaceutical students.
Published: August 30, 2005   
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