Ojbect:To study the effects of
Fufangdanshenfang on
Platelet Adhesion,Aggregation and
TXB 2、6 Keto PGF 1α in Blood Stasis Syndromes Model Rats.Methods:The rat blood stasis syndromes model was caused by subcutaneous injection of Adr and ice\|bathing.We studied the effects of Fufangdanshenfang on
platelet aggregation,adhesion,TXB 2 and 6 Keto PGF 1α in blood stasis syndromes model rats.Results:The results indicated that compared with normal rats,the platelet
Aggregation and
Platelet Adhesion were markedly increased.Fufangdancanfang was antagonized the increase of platelet adhesion and ADP\|induced platelet aggregation in model rats.Fufangdancanfang markedly increased the level of TXB 2\,6 Keto PGF 1α in plasma and the content of abdominal aorta tissue 6 Keto PGF 1α in model rats,but had little effect on the proportion of TXB 2/6 Keto PGF 1α .Conclusion:The results suggested that rat blood stasis syndromes model of Adr was caused successfully,and we inferred that the effects on the platelet aggregation and platelet adhesion might not be connected with the system TXB 2\|PGI 2.Fufangdancanfang was antagonized the increase of platelet adhesion and ADP\|induced platelet aggregation in model rats.
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