Objective:To investigate the response of electrogastrogram(EGG)of normals to waster,beer and
domperidone,and to study the
influence of different meals and
domperidone on EGG.Methods:EGG was recorded in ten healthy volunteers after fasting for twelve hours.The changes of EGG were recorded after fasting,drinking water and beer,and taking domperidone,
respectively.Results:Period dominant power(PDP)after fasting,drinking water and beer were(346.97±341.37)dB,(786.90±556.26)dB,(469.03±513.48)dB,respectively.PDP of drinking water and beer after taking domperidone were(945.89±568.64)dB and(893.38±538.60)dB,Water as well as domperidone induced a sigˉnificant postprandial increase(P<0.05),while beer induced a slight increase of the PDP above the fasting level.There was no statistical difference between PDP of drinking water and beer(P>0.05).Power ratio of drinking water and beer(after domperidone/fsting)was not significantly difˉferent(P>0.05).Conclusion:EGG changes seem to be dependent on the consistency,the caloric and nutrient composition of the testing meals.Domperidone can improve the intensity of gastric dynamic,which has no relationship with the meal constituency.