Early history of wound treatment. Clinical observations on the woundhealing properties of honey. Treatment of pressure sores.
Recent advances inthe
management of Fournier's gangrene: Preliminary observations. Accelerationof wound healing by topical application of honey. Speeding up the healing ofburns with honey. The use of honey in the treatment of infected wounds. Theantibacterial activity of honey. 1. The nature of the
antibacterial activity.The antibacterial activity of honey. 2. Variation in the potency of theantibacterial activity. A comparison of the sensitivity of wound-infectingspecies of bacteria to the antibacterial activity of manuka honey and otherhoney. Sudanese bee honey in the treatment of suppurating wounds. The use ofhoney in the treatment of chilblains, non-specific ulcers, and small wounds.Honey - its role in medicine. 3. Effect of heat. Wound healing properties ofhoney. The antimicrobial effect of honey in the management of septic wounds. Aclinical study of the topical use of bee honey in the treatment of some occulardiseases. Food allergy to honey: Pollen or bee products? Characterisation ofallergenic proteins in honey by means of immunoblotting. The effect ofgamma-irradiation on the antibacterial activity of honey.The use of honey and sugar for the treatment of ulcers in leprosy. Honeyand healing. Composition of honey. Chemical acidification of wounds. Anadjuvant to healing and the unfavourable action of alkalinity and ammonia. Thenumerous reports of the effectiveness of honey in wound management, includingreports of several randomised controlled trials, have recently been reviewed,rapid clearance of infection from the treated wounds being a commonly recordedobservation.In almost all of these reports honey is referred to generically, therebeing no indication given of any awareness of the variability that generally isfound in natural products. Since microbiological studies have shown more thanone hundred-fold differences in the potency of the antibacterial activity ofvarious honey, best results would be expected if a honey with a high level ofantibacterial activity were used in the management of infected wounds.The stimulation of tissue growth may be a trophic effect, asnutrification of wounds is known to hasten the healing process: the level ofthe wide range of micronutrients that occur in honey also varies.(In none of the clinical reports of use of honey on wounds was the honeyused sterilised.No case of infection resulting from the use of honey has beenreported.)The amount of honey needed depends on the amount of fluid exudingfrom the wound - the benefits of honey effect of honey in the management ofseptic wounds." 61-67.Honey-impregnated gauze versus amniotic membrane in the treatment ofburns. "Healing effect of floral honey and honey from sugar-fed bees onsurgical wounds (animal model)." Journal of Veterinary Medicine."Speeding up the healing of burns with honey.
Berliner Tierärztliche Wochenschrift Nr. Journal ofClinical Biochemistry and Nutrition 13 : 7-12.The effect of dilution on the rate of production of hydrogen peroxide inhoney. Honey bees appear in the temple and tomb art of Egypt as far back as2400 B.C. The honey bee was the symbol of Lower Egypt. In the solar cult of Ra,the tears of Ra were honey bees.