This paper discussed the status of soil P and K nutrient and their influencing factors in Tibet. The results showed the soil total phosphorus (TP) and total potassium (TK) content were both mainly determined by the parent material. In addition, TP in surface layer was higher than subsurface layer due to significant positive correlation between TP and OM, which showed the biological surface accumulation of phosphors. While, TK in surface layer was lower than in subsurface layer because of significant negative correlation between TK and OM, which indicated the "dilution effect" of OM to K. There was 78% of the soil area in Tibet that available P contents (AP) in the surface layer was lack, and the subsurface layer of that was lower. The relations of AP and TP, AP and OM were complicated, but the relation between AP and pH was close generally, especially higher in soil which pH was from 6.4 to 7.3. The area of soil available K contents (AN) which were 100~150 mg/kg and >150 mg/kg were 17% and 66% in Tibet, respectively. AK was influenced by CEC and OM, not relation with soil clay, and not influenced by TK.