GENETIC ENGINEERING
THIS IS THE SELECTION ,EXTRACTION AND INTRODUCTION OF A GENE INTO AN ORGANISM
WHICH RESULTS IN THE PRODUCTION OF A DESIRED CHARACTERIC OR PRODUCTS.
USEFUL PRODUCTS OF GENETICAL ENGINEERING
INSULIN AND HUMAN FACTOR VIII
HUMAN INSULIN IS A PROTEIN,PRODUCED BY THE BETA CELLSOF THE ISLETS OF LANGERHANS.INSULI IS INVOLVED IN BLOOD GLUCOSE LEVEL REGULATIO. IT IS THE ONLY HORMONE THA CONTROL THE RISE OF BLOOB GLUCOSE LEVEL,IT`S TARGET ORGAN IS THE LIVER.THE DEFICIENCY OF THIS IMPORTANT HORMONE LEADS TO DIABITIS MELLITUS.WHEN THE PRODUCTION OF INSULIN HAS CEASED THERE IS NEED TO INTRODUCES INSULIN FROM EXTERNAL SOURCES TO HELP KEEP THE GLUCOSE LEVEL CONSTANT.INSULIN CAN BE OBTAINRD FROM ANIMALS SUCH AS DOGS,CATTLE ,PIGS ETC,BUT IT REQUIRES LARGE QUANTITIES OF PANCREAS TO OBTAIN A MINUTE AMOUNT OF INSULIN.SINCE THE INSULI OBTAINED IS DIFFERENT FROM THE HUMAN INSULI,AND THE PROCESS IS VERY DIFFICULT SCIENTIST HAVE NOW TURNED TO GENETIC ENGINEERING FOR A SOLUTION.IN THE 1980`S ATTEMPT WERE MADE TO OBTAIN INSULIN FROM MICRO ORGANISMS.`HUMILINWSA LICENSED IN 1982 AND WSA PRODUCED FROM E.COLI THAT HAD BEEN GENETICALLY MODIFIED.SINE THEN YEAST(SACCHAROMYCES CEREVISAE)AND OTHER MICRBES HAVE BEEN USED.
ADVANTAGES OF GENETICALLY MODIFIED INSULIN
1.THE INSULIN IS THE SAME AS HUMAN INSULIN ,SO THE PATIENT DOES NOT SUFFER ADVERSE REACTION WHEN USING IT.
2.THE QUANTITIES CAN BE PRODUCED ON A LARGER SCALE TO MEET THE NEEDS OF THE HORMONE
3.PRODUCTION COSTS ARE MUCH LOWER,THER LARGE QUANTITIES CAN BE PRODUCED
4.ETHICAL AND RELIGIOUS OBJECTION OF USING ANIMAL ARE OVERCOMED.
HUMAN FACTOR VIII HEAMOPHILIACS SUFFER FROM A DEFECTIVE GENE THAT FAIL TO PRODUCE FACTOR AN IMPORTANT AGENT IN BLOOB CLOTTING.TRADITIONALLY IT WAS OBTAINED FROM BLOOD SERUM.LARGE AMOUNTS OF SERUM WERE PURIFIED TO OBTAIN THE CORRECT PROTEIN.THE RISK OF VIRUES (HIV IN PARTICULAR) WERE HIH,AND RESULTED IN MANY HEAMOPHILIAC CONTRACTING AIDS.HOWEVER GENETIC ENGINEERRING SILVED THIS,NOW A GENE WHICH CODES FOR THE PRODUCTION OF FACTOR VIII CAN BE SELECTED AND PLACED IN A MICROBE WHERE THE DESIRED PROTEIN IS MANUFACTURED.
BENEFITS OF GENETIC ENGINEERING
1.IMPROVED HEALTH CARE SYSTEM
2.MORE INSULIN TO DIBETICS
3.
THERE ARE MANY OTHER INVENTIONS MADE BY SCIENTIST WHICH ARE OF GREAT IMPORTANCE TO HUMANS THROUGH GENETIC ENGINEERING.THE UNDERSTANDING OF GENETIC HAVE LED TO THE IMPROVEMENT IN THE HEALTH SECTOR. SO LET APPLAUDE,AND SUPPURT SCIENTIST FOR THIS GREAT WORK .