MONOCLONAL ANTIBODIES (1) Book Abstract
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Published: April 15, 2007
Monoclonal antibodies are the substances produced by a single type of fused cell which have got exceptional purity and specificity. These are the important components of immune system. They are able to recognize and bind to a specific antigen. In Monoclonal antibody technology, tumour cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a hybridoma, which will continuously produce antibodies. Monoclonal antibodies recognize virtually any antigenic determinant. They attack only the target molecule and they discriminate between similar epitopes. Besides being highly specific, they provide basis for protection against pathogens. Monoclonal antibodies are currently being used in many diagnostic problems like: Identifying infectious agents Identifying tumours, antigens and auto-antibodies Measuring protein and drug levels in serum Typing blood and tissues Identifying the specific cells involved in the immune response identifying and quantifying hormones.
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