As development of biology water saving, getting more food for every drop is the aim in the water saving agriculture, water
use efficiency is the key research direction in future agriculture. There is a lot of different concepts among
drought resistance, water saving and
water use efficiency, there are different research dimensions and aspects in different science studying on drought resistance, water saving and water use efficiency. In the different area with different precipitation and water resource, there are different research key problems on drought resistance, water saving and water use efficiency, and different develop directions of water saving agriculture. From passive drought tolerance research turn to initiative drought resistance research, then turn to water saving research, and will turn to water use efficiency research in future. There is a increase tendency of water use efficiency in wheat evolution of high yield breeding program, so that is must to develop high water use efficiency breeding changed from drought tolerance and drought resistance breeding, because high water use efficiency breeding could combing drought resistance and high yield traits into one new variety. It is should be stressed that more every kinds of fertilizers should be put into low and middle yield field for getting high yield and water use efficiency.