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Shvoong Home>Medicine & Health>Determination of Lignans of Schisandra Medicinal Plants by HPLC Summary

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Determination of Lignans of Schisandra Medicinal Plants by HPLC

Article Abstract by: TsingHua    

Original Author: China Journal of Chinese Materia Medica
Objective: To determinate the contents of lignans in the stems, roots and fruits of Schisandra medicinal plants. Method:
HPLC was applied to determine the contents of schisandrin, gomisin A, schisantherin A, deoxyschizandrin, d-epigalbacine, (+)-anwulignan, wuweizisu B, 6- O -benzoylgomisin O and wuweizisu C in the stems, roots and fruits of Schisandra . Result: The percent contents of 9 lignans in the fruits of 5 species were 0.52%~1.96%, and 0.02%~1.51% in the stems of 11 species. The lignans in the fruits of S. micrantha were similar to that of S. sphenanthera , especially with high content of deoxyschizandrin. The lignans of S. viridis were similar to that of S. chinensis and with high content of schisandrin, gomisin A and wuweizisu B. (+)-Anwulignan was present in the fruits of S. henryi and S. sphenanthera , in the stems of S. micrantha and S. pubescens var. pubinervis , and in the roots of S. bicolor with percentages of 0.77%, 0.42%, 0.50%, 0.26% and 0.38% respectively. d-Epigalbacine was present in the stems of S. pubescens var. pubinervis , S. pubescens and S. glaucescens with percentages of 0.89% , 1.51% and 0.17% respectively. Conclusion: The lignans contents in the fruits of Schisandra were higher than that in the roots and stems. The fruits of S. henryi and S. sphenanthera , the stems of S. micrantha and S. pubescens var. pubinervis and the roots of S. bicolor , the stems of S. pubescens var. pubinervis , S. pubescens and S. glaucescens may be served as the resources plants of (+)-anwulignan and d-epigalbacine respectively.
Published: December 25, 2003
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