AIM: To observe the effects of
amygdalin in immunoloregulation. METHODS: Subcutaneous injection of Freund
adjuvant resulted in
atrophic gastritis models in rats,and then the free and total acidity and activity of pepsin in gastric juice were determined after
ig amygdalin for 6 months. Intradermal injection of Freund adjuvant caused
adjuvant arthrositis in rats after ig amygdalin for 7 d ,and then inflammatory
swelling of primary inflammatory and swelling percentage (%) and inhibition percentage (%) of recurrent inflammatory were determined as well as the indexes of clearance (K) and phagocytosis (α) by the
carbon granular clearance in mice after ig amygdalin for 7 d . RESULTS: The activity of pepsin in high dose group and middle dose group decreased (P< 0.05 ). The acidity of gastric juice of all groups had no significant difference (P> 0.05 ). Amygdalin could prevent adjuvant arthrositis in rats, and high and middle dose of amygdalins could inhibit inflammatory swelling (P< 0.01 ). K and α increased (P< 0.01 ) in high dose group, but K increased in middle dose group (P< 0.05 ). CONCLUSION: Amygdalin can regulate immunological function in animal models.
More abstracts about the Experimental study of effects of amygdalin on adjuvant inflammatory