Objective To study the effects of cadmium on the histopathological changes of sexual and accessory sexual glands in rats.
Methods \ all four groups rats were injected subcutaneously cadmium chloride at the doses of 0,0\^5,1,and 2 mg/kg body weight,respectively. Once a day and five days per week for 5 weeks. Results \ The results showed that blood and urinary cadmium concentrations increased and weight and volume of testis and
epididymis in the exposed rats decreased.
Seminiferous tubules became thinner,and epithelia arrange was disordered into strip\|shaped,cell layers in seminiferous tubules were reduced in the exposed rats.No sperm was found in seminiferous tubules of high dose groups.Epithelia cells of epididymis were the type like to low pillar and were arranged in mess.There were a lot of deformed sperm in the lumen.The size and thickness of tubes in seminal vessel and prostate were decreased in the exposed groups. Conclusion \ These indicated that cadmium could result in the decreased weight of sexual and accessory sexual glands and obvious histopathological changes of testis and epididymis in rat.