In this paper, the indexes and models are used to measure the accessibility of transport network, such as total transport distance Di and accessibility coefficient. On the basis of “The Shortest Route Model”, the evolution of railway network, changes of the spatial structure in accessibility, the relationship between railway network distribution and spatial economic growth in past hundred years in China are analyzed. The results show that the evolution of railway network in China experienced 4 stages, that are initial stage, constructing stage, extending and optimizing stage, but the speed of spatial expanding is relatively slow. Hundred years construction of railway leads to “Time-Space convergence”. The spatial structure of accessibility displays “different circles with one core”, and radiates from Huabei Region to surroundings. The area, higher than nationwide average level in accessibility, expands from North China to East China and Middle China, and the center of accessibility moved from Tianjin to Zhengzhou gradually. The construction of railway impulses the evolvement of social economic spatial structure, the modernization of transport corridor will impulse spatial economic agglomeration further