Objective To study the therapeutic mechanism of Yi Xin Le (YXL) oral liquid in chronic
fatigue syndrome. Methods Animal
model were prepared by application of complex stress factors. The animals were divided into blank group, fatigue model group, large YXL dosage group, small YXL dosage group and ass-hide glue compound group.
Immunoloregulation network IL-2, IFN, NK was studied. Results It showed that the network in animals of
Chronic Fatigue is obviously lower than that in normal animals, while IL-2, IFN, NK activity were obviously enhanced in the animal groups which were administered large or small YXL dosage and ass-hide glue compound group, which has a notable difference with the model group (P<0.05). Furthermore, the network in the three groups were recovered to the normal level, that is, the difference between them and the blank group is indistinctive (P<0.05). Conclusion The fall of activity of immunoloregulation network IL-2, IFN, NK may be one of the reasons of Chronic Fatigue Syndrome . Enhance and regulate of IL-2, IFN, NK level may be one of the mechanisms of YXL in treatment of chronic fatigue syndrome.