Objective In order to look for the natural anti-demodex mites drugs,we have investigated the anti-demodex effects of five creams made from five different plants
volatilizable oils in vitro under indoor temperature. Methods Under indoor temperature 18℃~26℃,and relative humidity 60%~70%, demodex mites were obtained from the forehead,cheek,and nose of outpatients in our dematological department or some healthy students in our college.Different creams were immediately added onto demodex mites and the survivals of demodex were observed under microscope. According to the results,the best drug was made into different gradient concentrations,and the anti-demodex effect was observed under microscope. Results The creams made from
Curcuma longa.L,
flos caryophylli,
eucalyptus globulus leaf,
zingiber coralliaum,
Litsea pungens Hemsl Volatilizable oils had anti-demadex effects.The mortality of the demodex increased higher as time went on.Curcuma cream has the best anti-demodex effect .There was remarkable differentiation in mortality and the changes of the morphologies and structures of mites between the curcuma cream and the basal cream(P<0.05).There were no remarkable differentiations among the Curcuma longa cream,Flos caryophylli cream,Eucalyptus globulus leaf cream,Zingiber coralliaum cream and Litsena pungens Hemsl cream(P>0.05). There were correlations between the anti-demodex and the gradient concentrations. Conclusion The volatilizable oils of Curcuma, Flos caryophylli,Eucalyptus globulus leaf,Zingiber coralliaum and Litsea pungens Hemsl have anti-demodex mites effects. Curcuma longa has the strongest anti-demodex mites effects.Our research work lays a foundation for clinical therapy of demodicidosis with Chinese medicine.
More abstracts about the Reseach of the anti-demodox mites effects of five creams made from five plants volatilizable oil