Objective: To study the effects of supplemented
Yang Supplementing Five Returning Decoction on the blood lipid and immune
function of the model mouse. Methods: Supplemented
Yang Supplementing Five Returning Decoction is composed of Yang Supplementing Five Returning Decoction,
Herba Epimedii and propolis. The effects of two formulae, Yang Supplementing Five Returning Decoction and Supplemented Yang Supplementing Five Returning Decoction on the blood lipid, the functions of nonspecific immunity, humoral immunity and cellular immunity were investigated on the normal and hyperlipemia rat models and immunosuppressive mouse model. Results: Supplemented Yang Supplementing Five Returning Decoction could not only maintain the original formula functions of lowering TC. TG and LDL C of rats ( P <0.05, P <0.01), but also obviously enhance the macrophage phagocytosis of mice ( P <0.05, P <0.001), thymus index ( P <0.001) and the actions of HC 50 ( P <0.01) and DTH ( P <0.05). Conclusion: Supplemented Yang Supplementing Five Returning Decoction can improve the above indexes of hyperlipemia and low immune function mice, and has the functions of Supplementing qi and nourishing blood, quickenning blood and transforming stasis, and supplementing kidney and invigorating yang.