In order to study the mechanism of the pulmonary ventilatory function improved by“Yang-Warming and Fluid-Dispersing
Formula”,rabbits were randomly divided into the control group(A),model group(B)and treatment group(C).In the model group and treatment group,the pathologic rabbit models with accumulation of cold fluid in the lung were set up by controlling the ventilatory volume,infusion of physiologic saline and leaving the models in cold environment.The treatment group was treated in imitation by“Yang-Warming and Fluid-Dispersing Formula”(“Minor Blue Dragon Decoction”plus Radix Ginseng and Radix Astragali)to determine and analyze the related indexes,such as respiration,heart rate,blood pressure,urine volume,change in at rerial blood gas,
plasma corticosteroid,change in aldosterone content,morphological change of the pulmonary tissues,etc.The results showed that in comparison between the treatment group and model group,PaCO2 of carotid blood was decreased(P<0.001),with elevation in PaO2.PH value,SBE(P<0.05),and plasma corticosteroid(P<0.05),and with drop in aldosterone(P<0.05).The conclusion is that“Yang-Warming and Fluid-Dispersing Formula”possesses the fuctions to dilate the bronchi,resist inflammation and promote urination to improve the pulmonary ventilation,which may be one of the mechanism in this formula for this syndrome.