Objective:To study the effect of
Qian Hui capsule on improving the movement of the stomach and small intestine.Methods:Qian
Hui capsule was administered ig to normal rats and the rats treated with neostigmine and atropine for 4 days once a day;domperidone served as controls.PSP(phenolsulfonphthalein)solution was givenig to each rat 30min after final administration and then they were Killed at intervals of 20min.The total and residual content of PSP in the stomach and different intestinal segments were determined;The determined data were used to calculate the percentage of stomachal ovacuation and the relative percentage of small intestine propulsion.Results:In normal group of rats.
Qian Hui capsule has more effective in improving
stomachal evacuation and small intestine movement than domperdione,exiting a significant diffierence(P<0.01)between Qian Hui capsule and domperidone.In the group of rats treated with neostigmine,it showed significnat difference between Qian Hui capsule and domperidone in improving the stomachal evacuation and in enhancing small intestine movement(P<0.01),but there was no significant difference in enhacing small intestine movement(P>0.05)between Qian Hui capsule and neostigmine.In the group of rats treated with atropine ,the signifficent difference was showed between Qian Hui capsule and domperidone in improving stomachal evacuation and small intestine movement(P<0.01).Conclusion:Qian Hui capsule is effective in improving stomachal evacuation and small intestine movement in normal rats and rats treated with neostigmine and atropine,which has more effective than domperidone.