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Shvoong Home>Medicine & Health>Effect of Qingdutuire decoction powder in treating endotoxic fever and its influence on plasma argin Review

Effect of Qingdutuire decoction powder in treating endotoxic fever and its influence on plasma argin

Article Review   by:TsingHua     Original Author: HEBEI MEDICAL JOURNAL
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Objective: To investigate the effect of Qngdutuire decoction powder(QDP) on endotoxie fever and itsinflueneon plasma arginine pitressin (AVP), endotoxin (ET ) and nitric oxidc (N0 ) levels. Meth0ds: 165 pationtswith endotoxic fever were randomly divided int0 2 groups: cither trcatment with QDP group(n = 12O) or antibioticgroup(n = 45), and 30 healthy volunteers served as controls. Changcs in plasma AVP, ET and NO lcvcls werc de-termined in patients before and after treatment. Results: There were significant differcnce betwecn thc QDP groupand the antibiotic group in cure rate and mean course of therapy(P < 0. O5 ). After QDP trcatmcnt, plasma AVP,ET and NO levels wcre(7. 09 ±O. 52pg/mL, 0. 12 t±0. 08EU/mL and 89. 03±14. 74μmol/L) respectively, whichwere significantly low comparcd with that prior to therapy(10. 46 ±0. 80pg/mL, 0. 47 ±0. 6EU/mL and 124. 6l ±l7. l9μmol/L boh P < 0. 01 ). After antibiotic treatment, plasma ET levels(0. 28 ± 0 . 05EU/ml,) wcrc significant-ly high compored tith that QDP group(0. l2 ± 0. 05EU/mL both P < 0. 01 ). Conclusions: QDP has a good effect onpatients with endotoxic fever. It also has regulatory effect on AVP, NO and ET. QDP is of bcnefit in reducing in-flammation , kill germ, allay a fever and eliminate end endotoxin in patients with endotoxie fever.
Published: October 15, 1999   
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