Objective To research the effects of Guiqi Decoction(GQD) on the erythrocyte immune function (EIF) of patients with active
pulmonary tuberculosis (APT) and its clinical curative effects. Methods 120 cases of APT were divided into GQD group (62 cases) and chemotherapeutical group (58 cases) randomly. The newly-diagnosed patients were treated with H.R.E.S. regimens and the return patients were treated with H.Z.K. 1321 Th. regimens. The first group were required to take GQD additionally, one dose per day. The treatment lasted two months on end .The erythrocyte immunity index, focus range and sputum tuberculosis bacillus change were observed before and after treatment , and were compared with the immunity index of a normal group of 30 healthy people. Results EIF of both groups were lower than that of the normal subjects ( P <0.01). The rosette rate of red blood cell C 3b receptor (RBC- C 3bRR) of two groups all increased before and after treatment ,while the rosette rate of red blood cell Ic receptor (RBC-ICR) changed little .RBC- C 3bRR of GQD group increased higher than that of chemotherapeutical group ( P <0.01) .The total curative effects (93.54%) of GQD group was significantly higher than that of chemotherapeutical group (44.829%)( P <0.005) .The sputum tuberculosis bacillus conversed negatively:44 cases of GQD group and 18 cases of chemotherapeutical group were observed ( P <0.005).Conclusion CQD can enhance the EIF and improve the curative effects of APT.