The tensile fracture location characterizations of the friction stir welded joints of the AA1050-H24 and AA6061-T6 Al alloys were evaluated in this study. The experimental results show that the fracture locations of the joints are different for the different Al alloys, and they are affected by the FSW parameters. When the joints are free of welding defects, the AA1050-H24 joints are fractured in the HAZ and TMAZ on the AS and the fracture parts undergo a large amount of plastic deformation, while the AA6061-T6 joints are fractured in the HAZ on the RS and the fracture surfaces are inclined a certain degree to the bottom surfaces of the joints. When some welding defects exist in the joints, the AA1050-H24 joints are fractured on the RS or AS, the AA6061-T6 joints are fractured on the RS, and all the fracture locations are near to the weld center. The fracture locations of the joints are dependent on the internal structures of the joints and can be explained by the microhardness profiles and defect morphologies of the joints.