Background: The related stastistics shows that 17.3% aged people were found suffering variable type of nephrology in routine periodic physical examination. But there is no specific therapy to treat aged nephrology. Thus it is necessary to carry out the research on aged nephrology. Purpose: To observe the efficacy of treatment of Baoshen Decoction to aged nephrology. Methods: 46 patients were treated with Baoshen Decoction for 4 weeks and assayed for creatine, triglyceride, and cholesterol in the blood and nitrogen in the urine before and after the treatment. Their symptoms and signs were recorded in detail. Results: The rate of efficacy of Baoshen Decoction to symptoms of asthenia of kidney was 84.6%, and the rate of turning the proteuria to negative was 84.6%. Systolic blood pressure was dropped 21.8±4.2mmHg, and creatine in the blood was dropped 41.4±28.0umol/L. Cholesterol, triglycreide in the blood was also dropped. Conclusions: Treatment of Baoshen Decoction could reduce the symptoms of asthenia of kidney and improve the life quality of the patients. It could reduce the level of blood pressure and createmia significantly, as well as proteuria efficiently. Thus it could protect the renal function well.