Objective: To study the antioxidation ac tivity and
protective effect of
ginger oil on DNA damage. Method: Chemical
lig ht assay was used to detect the oxygen radicals scavenging capacity of ginger oi l. The ery throcyte oxidation damage was induced by H 2O 2. The effect of
ginger oil on o xidative erythrocyte was observed by the colorimetric analysis assay, and the content of malondialdehyde (MDA) in rabit hepatocyte was measured. The anaylsis of DNA damage was made with single cell gel electrophoresis(SCGE) techique. Result: Ginger oil might de crease light value compared with control group and inhibited erythrocyte ox idation damage. Compared with that in control group, the degress of DNA damage reduced significantly in the protected groups. Ginger oil might decrease the con tent of MDA remarkably and inhitibition rate was 48.16%. Conclusion: Ginger oil has dominantive
protective effect on DNA damage induced by H 2O 2. Ginger oil might act as a scavenger of oxygen radical and might be us ed as an antioxidant.