Objective To evaluate the clinical efficacy and safety of
cefdinir in the treatment of acute bacterial infection. Methods Multicenter
randomized controlled clinial study of cefdinir and cefteram were given at a dose of 100～200mg tid for 7～14 days. Results 208 patients enrolled in the study were divided into two groups, 102
cases were treated with cefedinir and 106 cases with cefteram as control. The cure
rates of cefdinir and cefterom were 72.55% and 69.81%, the
effective rates were 96.10% and 92.45% respectively. As for respiratory
tract infection, the effective rates were 90.91% and 95.35%, cure rates 63.64% and 72.09%. For urinary tract infection, the effective rates were 100% and 90.91%, cure rates 87.10% and 72.73%; Skin and soft tissue infection, the effective rates 100% and 90% and cure rates 70.37%, 63.33% respectivly. Both agents were well tolerated, 7.26% and 8.15% of patients in the cefdinir and ceftream
groups respectively experienced adverse events. There were no statistical significant difference. Conclusion Cefdinir is safe and effective in the treatment of slight and moderate bacterial infections.
More abstracts about the Multicenter randomized controlled clinical study of cefdinir and cefteram