Objective To find out the use of
antimicrobial agents in the surgical
departments and its rationality so as to provide basis
for the formulation of regulations for the use of
antimicrobial agents in the hospital. Methods A retrospective investigation was made into 317 cases discharged from the surgical
departments. Results The utilization ratio of antimicrobial agents by inpatients from the surgical departments reached 90.3%, including 30.3% for treatment, 63.4% for prevention and 3% for mixed purposes. The use of antimicrobial agents, which could be classified into 12 groups and 43 kinds, amounted to 770 cases(times). 37.3% of the 278 cases used only one kind of antimicrobial agents and 62.7% more than one. The use of 2 kinds or 3 kinds, which also lasted for too long a time, dominated in the use of the agents for prevention, accounting for 52.2%. Only 11.4% of the agents used for treatment could be chosen with reference to pathogenic bacteria and the results of drug sensitive tests. Conclusion Working out regulations for the use of antimicrobial agents, stressing etiological examinations and choosing medicines according to the results of drug sensitive tests are of great significance to the reduction of the occurrence of drug resistant strains.