Objective To investigate the characteristics and clinical situation of adverse drug reactions in our hospital so as to promote
rational drug use.Method 437 ADR cases had been collected from March 13,1994 to October 17,2005 in our hospital.All the cases were analyzed in respect of drug species,involved organ systems,ways of administration,aspects of reporters and ages of the patients etc.Result Among the 437cases of ADR,the reasons were found to be related to use of antibacterial,the quality of the injection fluid of traditional Chinese medicine,ways of intravenous administration and the older age of the patients.47.59% of the ADR cases was induced by antibacterial and the traditional Chinese medicine.ADR were manifested as skin and local lesion.The severity ADR shouldn't be neglected.Conclusion The strengthening of ADR monitoring can ensure
safe medication.It is suggested that ADR monitoring work should be exactly carried out especially when antibiotic and the Chinese medicine injections be used,so as to reduce and avoid the occurrence of more severe ADR.