Objective To observe the effects of tonic
prescriptions on the growth of different cultivated cells in rats, and further
identify their mechanism for promoting growth of cells. Methods MTT method was used to observe the effect of tonic
prescriptions on the growth of in vitro cultivated cells in rats. Results All these tonic prescriptions(Sijunzi Tang, Siwu Tang, Bazhen Tang, Shiquan Dabu Tang ) could markedly promote the hepatocyte, cardiac muscle cell and brain cell growth in rats (P<0.05); Siwu Tang was better than Sijunzi Tang in promoting growth of hypoxic hepatocyte for 2 weeks(P<0.05). The difference between 2- week group and 1-week group of cardiac muscle cells treated with Sijunzi Tang and Shiquan Dabu Tang was statistically significant(P<0.05). The effect of Bazhen Tang and Shiquan Dabu Tang was higher than Sijunzi Tang and Siwu Tang for promoting of brain cell growth (P<0.05). Conclusion Tonic prescriptions have marked effect on promoting growth of cells, otherwise,
different tonic prescriptions has different effects on promoting growth in different cells and their effects are closely related to types and growth stages of cells.