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Shvoong Home>Medicine & Health>An Experimental Study on Anti-inflammation, Expectorant andAntibacterial Activities ofT. chinensis Summary

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An Experimental Study on Anti-inflammation, Expectorant andAntibacterial Activities ofT. chinensis

Article Abstract by: TsingHua    

Original Author: Chinese Journal of Ethnomedicine and Ethnopharmacy
This abstract was translated from 开口箭祛痰、抗炎及抑菌实验研究
Objective: To study anti- inflammation, expectorant and an tibacterial activities of T. chinensis in Hubei. Method: Phenosulfon
phthalein e xcretion (PSP) test to observe the expectorant effect; the ear inflammation indu ced by dimethylbenzene in mice and DTH induced by DNCB in mice to evaluate the a nti-inflammation activity; MIC was determined by 2-fold broth dilution method; t heKarber measure to determine the acute toxicity of T. chinensis. Result: 14.9, 7.5 and 3.8 g/Kg of T. chinensis showed significant expectorant action, signifi cant inhibitory action towards acute inflammation induced by dimethylbenzene epi dermidis, weak antianaphylaxis action in the DTH induced by DNCB in mice; The an tibacterial result test in vitro showed that T. chinensis can significantly inhi bit Staphylococcus aureus?Staphulococcus epidermidis and Pseudomonas aeruginosa (MIC:31.3 g·1-1,),and also inhibit beta streptococcus(MIC:125 g·1-1);The ac ute toxicity experiment showed that the LD50 is 148.7 g/Kg crude drugs. Conclusi on: T. chinensis showed significant activities of expectoration, anti-inflammati on, and definite Antibacterial action. Furthermore, its toxicity is low.
Published: April 30, 2005
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