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Shvoong Home>Medicine & Health>Study the Effect on Anti-oxidation in Hyperlipidemia Rats by Uniform Design of Combination of Effect Summary

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Study the Effect on Anti-oxidation in Hyperlipidemia Rats by Uniform Design of Combination of Effect

Article Abstract by: TsingHua     

Original Author: Liaoning Journal of Traditional Chinese Medicine
Objective:Study the relationship between combination of effective parts extracted from Polygonatum,Polygonum and the anti
oxidation in hyperlipidemia rats. Methods: The rats were divided into normal control group,model group and treatment group.Make use of biochemistry method to surve biochemistry index of each group of the rats.The data were analyzed by ANOV and multi comparison,and obtained the optimization results by regression and calcuation of Good Lattice Point. Results: Compared with model group,NO of 3 treatment groups,MDA of 8 treatment groups,GSH Px of 6 treatment groups,SOD of 5 treatment groups and TAo of 4 treatment groups are significant ( P< 0 05) ;Compared with control group,GSH of 5 treatment groups,GSH Px of 2 treatment groups,SOD of 4 treatment groups and TAo of 4 treatment groups are significant( P <0 05);NO,MDA and CAT of 8 treatment groups are almost not significant ( P> 0 05). Conclusion :The different combination of effective parts of Polygonatum and Polygonum shows the different effect on anti oxidation hyperlipidemia rats.It is very necessary to study the relationship relevant to amount of effective parts and their effect so that we can get better Chinese drug scientifically and reasonably.
Published: May 18, 2005
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