The test of that acidic bovine neuropeptide 1 (ABNP 1) inhibited the
erecting tail of mice induced by morphine
had been done.The result showed that 0.5 g/kg of ABNP 1 can
inhibited 100% of the
erecting tail of mice induced by 100 mg/kg of morphine.0.25 g/kg of ABNP 1 can inhibited 50% of the erection tail of mice induced by 100 mg/kg morphine.0.125 g/kg of ABNP 1 can inhibited 10% of the erecting tail of mice induced by 100 mg/kg morphine.This indicates that ABNP 1 can inhibit the excitement of morphine.At same time,the test of the addiction of mice induced by ABNP 1 had also been done.0.50,0.25 and 0.125 g/(kg·d) of ABNP 1 were injected into each mouse respectively,and ABNP 1 was constantly given mice in 10 days.Then,5 mg/kg of nalxone was injected in to a mouse.The result showed that no mouse jumped from the gangplank.This indicates ABNP 1 is no addiction at this test concentration.