Objective:To observe and compare the anti inflammatory,antipyretic and diuretic effects of three kinds of Tongcao(Tongtuomu,Panyezhangyeshu
and Luosan)and seven kinds of
Xiao tongcao(Ximashanjinjiehua,Xinanxiuqiu①②,Ditanghua,Suixuezhangcai,Qingjiaye and Zhongguo jinjiehua).Method:Decoctions prepared from the above kinds of Tongcao and Xiao tongcao crude drugs were given to rats at dosages of 8g/kg and 4g/kg by ig.Pharmacological actionswere observed by means of carrageenan induced swelling paws,fever models induced by beeryeast or carrageenan and metabolic cage method in rats.Result:All the experimental decoctions could inhibit carrageenan induced swelling of rat paws in different degrees and exerted anti pyretic effect on rat fever models induced by beeryeast or carrageenan.Three kinds of Xiaotongcao(Ximashanjingjiehua,Xinanxiuqiu②,Zhongguojinjiehua)had obvious diuretic effect on rats.Conclusion:Decoctions of different species of Tongcao and Xiao tongcao all have anti inflammatory,
antipyretic and diuretic effects,thus providing some pharmacologic basis for the efficacy assay,clinical application,species collation and quality study of Tongcao and Xiao tongcao.