Effect of Chitosan on 30Day Survival Rate of Irractiated Mice

One hundred and twenty mice were divided into three experimental groups,drugged and irradiated group(CTS+I),irradiated and drugged group(I+CTS),drugged, irradiated and drugged group(CTS+I+CTS).The mice in every group were divided into four groups,control group of only irradiation,the group of 125,250and 500mg/kg.The effect of Chitosan(CTS)on the survival rate,average survival time and protection index of every period was observed aftcr each group mice were exposed to 60GY Xray.The results showed that the CTS made the survival rate,the average survival time and the protection index increased significantly.There were significant difference compared with control group.(P<005,P<001).The most effective one was the (CTS+I)group in all groups.The survival rate was 100%,80%and 70% in 10d,20d and 30d.And it was 70%,10% and 0% in the control group.The result suggested that the CTS can get a better cffect of absorbing Xray and caneel freeradical,drugged before irraidiation.So the suvival rate of mice were increased.