Turmeric has been used for centuries in Indonesia and India as a traditional medicine. Lately, more and more scientific evidence of the benefits of turmeric. One of the most promising research is the efficacy of turmeric to help the recovery of stroke patients.
Pamor turmeric seems to be more brilliant future. Modern medicine increasingly intensive research for the treatment efficacy of turmeric. Finally, gives another the news that a drug derived from turmeric can help the body repair the damage immediately after a stroke.
Researchers from Cedars-Sinai Medical Center in Los Angeles, USA, is currently preparing to conduct experiments on humans after receiving the results of saffron for the treatment of stroke research is promising. The results had been disseminated in the international stroke conference of the American Heart Association recently.
Drugs derived from turmeric that it can reach the brain cells and reduces muscle and movement problems in stroke patients. "There is great need for new treatments that can protect brain cells after a stroke and speed up recovery. This is the first major study showing the benefits of turmeric for stroke patients by encouraging the growth of new cells and prevent the death of brain cells after a stroke," said DR . Sharlin Ahmed from The Stroke Association, as quoted by the BBC website
The results seemed promising. However, DR. Ahmed said the result was still too early and need to be tested on humans to get more convincing results.
So far there is only one drug approved for the treatment of ischemic stroke caused by blockage of blood flow to the brain. The drug, known as tissue plasminogen activator (tPA). The drug was injected through the blood vessels to open blockages and restore blood flow in the brain.
Naturally, curcumin, the component in turmeric can not pass through the brain barrier that protects the brain from potentially toxic molecule. However, U.S. researchers succeeded in making modifications of curcumin with a new version of CNB-001 can pass through obstacles in the brain. Laboratory tests on rabbits to open the results of the modified curcumin might be effective until three hours after stroke in humans.
Research leader, Dr. Paul Lapchak, said the drug seemed to keep brain cells alive after a stroke. A stroke kills brain cells because the brain is deprived of blood containing oxygen. This sparked a chain reaction that would expand the area of damaged brain. This result in increased disability suffered by stroke patients.
CNB-001 Modification of curcumin is looking to improve four "signal path" which gave "food" brain cells neurons. The drug was not going to target the blood clot. In this study when given to guinea pigs, in one hour or three hours in the human body, the drug reduces the problem of muscle and control movement caused by stroke.
Earlier, in 2008, there are also studies that prove that turmeric can shrink the size of haemorrhagic stroke. Jay McCracken, a medical student working with neuroscientist from the Medical College of Georgia, Dr. Krishnan Dhandapani, research animal model to see the effects of curcumin on intracerebral hemorrhage, bleeding in the brain caused by vessel rupture.
Patients with this type of hemorrhagic stroke often have symptoms of headaches. According to the American Stroke Association, about 17 percent of bleeding strokes occur in those who have high blood pressure.
"We found that curcumin significantly decreases the size of blood clots, but do not yet know why this happens," McCracken said.
He suspects it is because curcumin is antipembengkakan and antioxidant substances. For the study, he dissolved the yellow turmeric powder in corn oil and injected in the stomach of animals.
The researchers believe that turmeric can prevent a stroke. They continued the study and make turmeric in tablet form for those at risk.