U.S. scientists have shown that ovary stem-cells can produce oocytes. This study challenges the dogma that the release of eggs from the ovaries, being non-renewable, is limited in time. Hence, when the Menopause starts, a decrease or a discontinuation of production by the ovaries are observed. Recent works are published in the review Nature Medicine. They resume the 2004 study by researchers at Massachusetts General Hospital who focused on the ability of female mice to produce eggs in adulthood. Indeed, the hypothesis which seems assuming and implausibly, has not resurfaced in the last five years. Remained open, the study focused on mice and the results seemed irrefutable. That''s why Jonathan Tilly and his team began to work closely with the motivation to prove that their work was realistic. It shows the reversal of the paradigm with the determination of the team that has made felt in the development of a new protocol: human germ cells are isolated from the ovaries, labeled with green fluorescent protein and then, transferred in human ovarian tissue biopsied. It is grafted under the skin of a female mouse. The results are convincing: oocytes are released, some of which are colored green. Which induces it was cells from the ovarian tissue (green color). Moreover, those that were not marked were part of human ovarian tissue biopsied and reimplanted. Accordingly, the results show that ovary stem-cells are producing eggs. It is now time to determine when ovaries may be active. For now, further work is underway to determine if the oocytes are functional and more precisely how they are released.