OSTEOARTHRITIS~~GLUCOSAMINE PLAY AN IMPORTANT ROLE IN TREATMENT OF OSTEO ARTHRITIS Osteoarthritis is very common chronic degengerative disease.it involves every joint of the body.in this degenration of
cartilage in the joints occurs.this is an inflammatory disease in which joint begins to wear out .that is break down of cartilage increased , cartilage is made up of collegen fibres, glycoproteins,and proteoglycans GLYCOSAMINE PLAY AN IMPORTANT ROLE IN TREATMENT OF OSTEOARTHRITIS PATIENT suffering from degenerative arthritis need to take a potent , well balanced anti oxidant and
mineral supplement.strong evidence suggest that pt. Suffer from this disease are deficient of several antioxidant and supporting
nutrient such as
vitamine D, C , E and boron and vitamine B3
GLUCOSAMINE IS ONE OF THE BASIC NUTRIENT FOR THE SYNTHESIS OF CARTILAGE.IT IS A SIMPLE AMINO SUGAR THAT IS PRIMARY BUILDING BLOCK OF PROTEOGLYCANS, WHICH ARE THE MOLECULE THAT GIVE CARTILAGE ITS ELASICITY.UNLIKE nsaidsAND ASPIRIN , GLUCOSAMINE DOESN’T SIMPLY COVER UP PAIN BUT RATHER HELP TO REBUID THE DAMAGED CARTILAGE. In1999 a three year , large , randomized- sample , placebo-controlled,double- blind clinical trialwas reported at the manual meeting of the AMERICAN COLLEGE OF RHEUMATOLOGY.this study shows that glucosamine not only reduced the pain and inflammationpf arthritis but actually stopped the deterioration of the cartilage.what was even more impressive was the fact that there was evidence of actual cartilage regrowth ,,,,,,,,in one case. On the other hand the plcebo group members, who took the traditional
nsaids ;continued to experience rapid deterioration of their joints. This study has shown the significant health benefit for arthritis patients who take glucosamine
sulfate supplements in the 1,500-2,000- mg range, with no side effect.even more exciting is the fact that when the patient in the clinical trial discontinued their glucosamine , the pain didn’t return for weeks and even months later.. NSAIDS, on the other hand ; have significant side effect such as ulcer, upper gi bleeding and possible liver damage….this drugs nothing to slow down the degenerative process but in fact may acclerate it In acute cases we prescribe NSAIDS but for long term treatment glucosamine sulfate play an invaluable role . Dr should prescribe antioxidant capsule,minerals, essential fats, and grape seed extract, along with GLUCOSAMINE SULFATE
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