Slope land is both the main erosion source of soil and water loss and the important land resource in Guangdong province. The study on the soil erosion of the slope land is very significant to the sustainable utilization of the slope land. According to the soil erosion of the sustainable utilization of the slope land and the investigation on the typical region of soil and water loss in Guangdong, the present situation of the utilized slope land and its soil erosion are systematically expounded, and the slope land degradation due to the soil erosion is discussed. The influenced factors of the soil erosion on the slope land are analyzed, and some countermeasures of controlling the soil erosion of slope land are put forward in this paper. The soil erosion area of the slope land in Guangdong is 1.14×10~4km~2, accounting for 79.74% of the total erosion area. The intensity of erosion is light and medium. The soil erosion yield is 8 540.67×10~4 t/a, the modulus is from (7 215.68) to 7 335.56t/(hm~2·a) and the depth is from 5.4mm/a to 5.6mm/a. As a result of the serious soil erosion, the slope land degradation such as shallow soil layer, deterioration of soil properties and vegetation degradation appear in the place, the sustainable utilization of the slope land will be restricted seriously. The main causes of the slope land degradation include rainfall, thick weathering crust, slope and human active factors and among them the best important one is human activity factor. In order to solve the problems in soil erosion of the slope land, the attention should be paid to some ways such as vegetation restoration, vegetation project measures, and soil and water conservation farm and watershed comprehensive controls in the slope.