AIM: To find out bioactive compounds of Ocimum basilicum L METHOD: The chemical constituents were isolated by various
column chromatograpic methods The
structures of these compounds were elucidated by spectral analysis RESULT: Seventeen compounds were obtained and the structures were identified as Quercetin(1),(17 R ) 3β Hydroxyhexanordammaran 20 one(2),Quercetin 3 O β D galactoside(3),Quercetin 3 O β D glucoside 2′′gallate(4),Isomyricitrin(5),Quercetin 3 O β D glucoside(6),
Kaempferol 3 O β D glucoside(7),Hexadecanoic acid 2,3 dihydroxypropyl ester(8),Rutin(9),Quercetin 3 O (2′′ O galloyl) rutinoside(10),Quercetin 3 O α L rhamnoside(11),Syringin(12),(6 S,9S ) Roseoside(13),Kaempferol(14),7 hydroxy 6 methoxy coumarin(15),β Sitosterol(16) and Daucosterol(17) CONCLUSION: Compound 2 is a new compound Compounds 1,3,4,5,7,8,10,11,12,13 and 15 were isolated from this genus for the first time Anti PTP1B activities of all compounds were tested,the IC50 value of 1 was 23 3 μmol/L and other compounds had no activities